TY - JOUR
T1 - Detection of human papillomavirus type 18 DNA in squamous cell carcinoma developing from Bowen's disease of the face
AU - Deguchi, Masotoshi
AU - Tomioka, Yoshihisa
AU - Okuguchi, Jyun Ya
AU - Mizugaki, Michinao
AU - Tagami, Hachiro
N1 - Copyright:
Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.
PY - 1997
Y1 - 1997
N2 - We have detected human papillomavirus type 18 DNA in squamous cell carcinoma developing from Bowen's disease of the face in a 78-year-old Japanese female farmer. Despite negative results with in situ hybridization performed with one generic biotin-labelled DNA probe that can detect HPV types 6, 11, 16, 18, 31, and 33, the polymerase chain reaction (PCR) with HPV type 18 primer detected the presence of HPV DNA. As far as we know, this is the first report of the detection of HPV type 18 DNA in the lesional skin of Bowen carcinoma in the general population. The prevalence of HPV infection in squamous cell carcinoma developing from Bowen's disease may be higher than we expected.
AB - We have detected human papillomavirus type 18 DNA in squamous cell carcinoma developing from Bowen's disease of the face in a 78-year-old Japanese female farmer. Despite negative results with in situ hybridization performed with one generic biotin-labelled DNA probe that can detect HPV types 6, 11, 16, 18, 31, and 33, the polymerase chain reaction (PCR) with HPV type 18 primer detected the presence of HPV DNA. As far as we know, this is the first report of the detection of HPV type 18 DNA in the lesional skin of Bowen carcinoma in the general population. The prevalence of HPV infection in squamous cell carcinoma developing from Bowen's disease may be higher than we expected.
KW - Human papillomavirus
KW - In situ hybridization
KW - Polymerase chain reaction
KW - Skin cancer
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M3 - Article
AN - SCOPUS:0030810186
VL - 7
SP - 487
EP - 488
JO - European Journal of Dermatology
JF - European Journal of Dermatology
SN - 1167-1122
IS - 7
ER -