Detection of exhaled CO as a simple non-invasive tool for monitoring acute exacerbations of asthma in the elderly

T. Ohrui, M. Yamaya, N. Yamada, S. Okinaga, M. Yanai, H. Sasaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Exhaled carbon monoxide (CO) concentrations were measured on a CO monitor by vital capacity maneuvers in asthmatic patients either receiving or not receiving inhaled corticosteroids, and in nonsmoking healthy control subjects. CO was detectable and measured reproducibly in the exhaled air of all subjects. The exhaled CO concentrations were higher in asthmatic patients not receiving inhaled corticosteroids and similar in asthmatic patients receiving inhaled corticosteroids and nonsmoking healthy control subjects (Am J Respir Crit Care Med 1997: 156: 1140-1143). All patients with inhaled corticosteroid treatment had reductions in exhaled CO concentration and eosinophil cell counts in sputum that were accompanied by an amelioration of airway obstruction. These results showed that detection of exhaled CO could be a simple non-invasive tool for monitoring airway inflammation and acute exacerbation of asthma.

Original languageEnglish
Pages (from-to)484-486
Number of pages3
JournalNippon Ronen Igakkai zasshi. Japanese journal of geriatrics
Volume38
Issue number4
DOIs
Publication statusPublished - 2001 Jul

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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