Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes

Tadatsugu Imamura; Akira Suzuki; Socorro Lupisan; Taro Kamigaki; Michiko Okamoto; Chandra Nath Roy; Remigio Olveda; Hitoshi Oshitani

doi:10.1111/irv.12206

Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes

Tadatsugu Imamura, Akira Suzuki, Socorro Lupisan, Taro Kamigaki, Michiko Okamoto, Chandra Nath Roy, Remigio Olveda, Hitoshi Oshitani

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.

Original language	English
Pages (from-to)	21-24
Number of pages	4
Journal	Influenza and other Respiratory Viruses
Volume	8
Issue number	1
DOIs	https://doi.org/10.1111/irv.12206
Publication status	Published - 2014

Keywords

Enterovirus 68
Pediatric pneumonia
Viremia

ASJC Scopus subject areas

Epidemiology
Pulmonary and Respiratory Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/irv.12206

Cite this

@article{77759328907b4d478163a13c572d1401,

title = "Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes",

abstract = "Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.",

keywords = "Enterovirus 68, Pediatric pneumonia, Viremia",

author = "Tadatsugu Imamura and Akira Suzuki and Socorro Lupisan and Taro Kamigaki and Michiko Okamoto and Roy, {Chandra Nath} and Remigio Olveda and Hitoshi Oshitani",

year = "2014",

doi = "10.1111/irv.12206",

language = "English",

volume = "8",

pages = "21--24",

journal = "Influenza and other Respiratory Viruses",

issn = "1750-2640",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes

AU - Imamura, Tadatsugu

AU - Suzuki, Akira

AU - Lupisan, Socorro

AU - Kamigaki, Taro

AU - Okamoto, Michiko

AU - Roy, Chandra Nath

AU - Olveda, Remigio

AU - Oshitani, Hitoshi

PY - 2014

Y1 - 2014

N2 - Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.

AB - Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.

KW - Enterovirus 68

KW - Pediatric pneumonia

KW - Viremia

UR - http://www.scopus.com/inward/record.url?scp=84890860980&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890860980&partnerID=8YFLogxK

U2 - 10.1111/irv.12206

DO - 10.1111/irv.12206

M3 - Article

C2 - 24209770

AN - SCOPUS:84890860980

SN - 1750-2640

VL - 8

SP - 21

EP - 24

JO - Influenza and other Respiratory Viruses

JF - Influenza and other Respiratory Viruses

IS - 1

ER -

Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this