Detection and identification of non-Candida albicans species in human oral lichen planus

Mika Masaki, Takuichi Sato, Yumiko Sugawara, Takashi Sasano, Nobuhiro Takahashi

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Candida species were detected and identified in samples from the buccal mucosa, dorsal surface of the tongue and supragingival plaque of subjects with oral lichen planus (OLP). The Candida in the samples were cultured on selection agars, and identified by sequence analyses of 18S, 5.8S and 25/28S rRNA. The isolation frequency of Candida was higher in subjects with OLP than in those with healthy oral mucosa. Non-C. albicans were only isolated from people with OLP. These results support the notion that subjects with OLP are more likely to have oral colonization with Candida, and that non-C. albicans are specifically present in subjects with this condition.

Original languageEnglish
Pages (from-to)66-70
Number of pages5
JournalMICROBIOLOGY and IMMUNOLOGY
Volume55
Issue number1
DOIs
Publication statusPublished - 2011 Jan

Keywords

  • Candida
  • Microflora
  • Oral lichen planus
  • Polymerase chain reaction

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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