TY - JOUR
T1 - Desmoplastic melanoma arising in the ankle
AU - Hatori, Masahito
AU - Watanabe, Mika
AU - Watanabe, Hiroshi
AU - Hosaka, Masami
AU - Kokubun, Shoichi
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - Desmoplastic melanoma (DM) is an uncommon but potentially devastating malignancy that can be cured with early recognition and surgery. DM often occurs in elderly men and develops on sun-exposed areas with the head and neck being the most common site of origin followed by the extremities and trunk. We report a rare case of DM occurring in the ankle in an 85-year-old woman. Magnetic resonance imaging of the affected ankle showed a 4.3 x 4.3 x 2.5 cm sized mass which was located in the subcutaneous region, attached to lower leg muscles, the fibula, and the calcaneus. No metastasis to the lung, liver, bones or abdominal lymph nodes was found. In spite of below knee amputation, the patient died of lung metastases 10 months after surgery. Among several factors causing early death of the patient, a large size, a deep location and rapid growth of the tumor seem to be most important.
AB - Desmoplastic melanoma (DM) is an uncommon but potentially devastating malignancy that can be cured with early recognition and surgery. DM often occurs in elderly men and develops on sun-exposed areas with the head and neck being the most common site of origin followed by the extremities and trunk. We report a rare case of DM occurring in the ankle in an 85-year-old woman. Magnetic resonance imaging of the affected ankle showed a 4.3 x 4.3 x 2.5 cm sized mass which was located in the subcutaneous region, attached to lower leg muscles, the fibula, and the calcaneus. No metastasis to the lung, liver, bones or abdominal lymph nodes was found. In spite of below knee amputation, the patient died of lung metastases 10 months after surgery. Among several factors causing early death of the patient, a large size, a deep location and rapid growth of the tumor seem to be most important.
KW - Ankle
KW - Desmoplastic melanoma
KW - Magnetic resonance imaging
KW - S100
UR - http://www.scopus.com/inward/record.url?scp=31144474311&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=31144474311&partnerID=8YFLogxK
U2 - 10.3109/2000-1967-072
DO - 10.3109/2000-1967-072
M3 - Article
C2 - 16454164
AN - SCOPUS:31144474311
VL - 110
SP - 251
EP - 258
JO - Upsala Journal of Medical Sciences
JF - Upsala Journal of Medical Sciences
SN - 0300-9734
IS - 3
ER -