Designing biocompatible Ti-based amorphous thin films with no toxic element

Delin Zhao, Chunlin Chen, Kefu Yao, Xuetao Shi, Zhongchang Wang, Horst Hahn, Herbert Gleiter, Na Chen

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


We developed an amorphous Ti-Si-O thin film without any harmful element. Studies of the cellular response to this amorphous layer show that its cytocompatibility is comparable to a pure Ti used as a reference material. Meanwhile, the deposition of this amorphous thin film on a patterned Si surface was found to effectively modify the cellular behaviors, including cell attachment and cell proliferation. The development of such biocompatible TiSiO thin film with no toxic element provides new insights into the potential applications of amorphous materials in biomedical fields.

Original languageEnglish
Pages (from-to)142-147
Number of pages6
JournalJournal of Alloys and Compounds
Publication statusPublished - 2017 Jun 15
Externally publishedYes


  • Amorphous thin films
  • Biocompatibility in vitro
  • Metallic glass
  • Silicon
  • Ti oxide

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering
  • Metals and Alloys
  • Materials Chemistry


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