Design of stimuli-responsive nano boxes with chaperonins

Hisae Kuwagaki, Kazushi Kinbara, Hideki Taguchi, Masasuke Yoshida, Takuzo Aida

Research output: Contribution to conferencePaperpeer-review

Abstract

Chaperonin GroEL undergoes a large conformational change in response to ATP. We prepared new mutant GroELs, CA-R231C and CA-K311C+L314C, where cystein residues exist around the entrance the cavity. Fluorescent units were introduced to the mutants through the reaction of the thiol of cystein group with maleimide group of the fluorescent molecule. The optical properties of thus modified GroELs will be reported.

Original languageEnglish
Pages4959-4960
Number of pages2
Publication statusPublished - 2005 Dec 1
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: 2005 Sep 202005 Sep 22

Other

Other54th SPSJ Symposium on Macromolecules
Country/TerritoryJapan
CityYamagata
Period05/9/2005/9/22

Keywords

  • ATPase
  • Chaperonin
  • Fluorescent molecule

ASJC Scopus subject areas

  • Engineering(all)

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