Design of chemical glycosyl donors: Does changing ring conformation influence selectivity/reactivity?

Hiroko Satoh, Shino Manabe

Research output: Contribution to journalArticlepeer-review

59 Citations (Scopus)

Abstract

This tutorial review focuses on the design of glycosyl donors, especially on attempts to control selectivity/reactivity by employing bulky substituents, cyclic protecting groups, or bridged structures. These structural modifications are performed to change the conformational distributions of pyranoside/furanoside rings. We also briefly discuss this issue with regard to studies on furanosides and enzymatic glycosylation reactions. Readers will find that some of the designed glycosyl donors have been used to achieve total syntheses of natural products.

Original languageEnglish
Pages (from-to)4297-4309
Number of pages13
JournalChemical Society Reviews
Volume42
Issue number10
DOIs
Publication statusPublished - 2013 Apr 29
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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