Design concept and elemental technologies of the helical flow total artificial heart

Yusuke Abe, Takashi Isoyama, Itsuro Saito, Terumi Yurimoto, Shintaro Hara, Xin Yang Li, Haruka Murakami, Yukino Kawase, Masami Sato, Yusuke Inoue, Toshiya Ono, Kyoko Fukazawa, Kazuhiko Ishihara, Madoka Takai, Minoru Ono

Research output: Contribution to journalArticlepeer-review

Abstract

We have been developing a total artificial heart (TAH) named the helical flow TAH (HFTAH) using helical flow pumps (HFPs). The HFTAH was designed to have a small size with enough performance, good durability and good anatomical fitting. The left and right HFPs were designed separately so that they could be applied also for bi-ventricular or single ventricular assist devices. The elemental technologies are hydrodynamic levitation impeller, 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coating and absolute pressure sensor integration in the pump. The HFTAH was implanted in goats and 100 days survival was obtained. With animal experiments, the problem that hydrodynamic bearing touched to the shaft and was worn by the sucking effect was occurred. However, the potential of the HFTAH was demonstrated. We are expecting that the HFTAH would be an excellent total artificial heart as a next generation device.

Original languageEnglish
Pages (from-to)OS-1-OS-2
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume52
DOIs
Publication statusPublished - 2014 Aug 17

Keywords

  • Absolute pressure sensor
  • Helical flow pump
  • Hydrodynamic bearing
  • Total artificial heart
  • Ventricular assist device

ASJC Scopus subject areas

  • Biomedical Engineering

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