Design concept and elemental technologies of the helical flow total artificial heart

Yusuke Abe; Takashi Isoyama; Itsuro Saito; Terumi Yurimoto; Shintaro Hara; Xin Yang Li; Haruka Murakami; Yukino Kawase; Masami Sato; Yusuke Inoue; Toshiya Ono; Kyoko Fukazawa; Kazuhiko Ishihara; Madoka Takai; Minoru Ono

doi:10.11239/jsmbe.52.OS-1

Design concept and elemental technologies of the helical flow total artificial heart

Yusuke Abe, Takashi Isoyama, Itsuro Saito, Terumi Yurimoto, Shintaro Hara, Xin Yang Li, Haruka Murakami, Yukino Kawase, Masami Sato, Yusuke Inoue, Toshiya Ono, Kyoko Fukazawa, Kazuhiko Ishihara, Madoka Takai, Minoru Ono

PreClinical Research Center

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We have been developing a total artificial heart (TAH) named the helical flow TAH (HFTAH) using helical flow pumps (HFPs). The HFTAH was designed to have a small size with enough performance, good durability and good anatomical fitting. The left and right HFPs were designed separately so that they could be applied also for bi-ventricular or single ventricular assist devices. The elemental technologies are hydrodynamic levitation impeller, 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coating and absolute pressure sensor integration in the pump. The HFTAH was implanted in goats and 100 days survival was obtained. With animal experiments, the problem that hydrodynamic bearing touched to the shaft and was worn by the sucking effect was occurred. However, the potential of the HFTAH was demonstrated. We are expecting that the HFTAH would be an excellent total artificial heart as a next generation device.

Original language	English
Pages (from-to)	OS-1-OS-2
Journal	Transactions of Japanese Society for Medical and Biological Engineering
Volume	52
DOIs	https://doi.org/10.11239/jsmbe.52.OS-1
Publication status	Published - 2014 Aug 17

Keywords

Absolute pressure sensor
Helical flow pump
Hydrodynamic bearing
Total artificial heart
Ventricular assist device

ASJC Scopus subject areas

Biomedical Engineering

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10.11239/jsmbe.52.OS-1

Cite this

Abe, Y., Isoyama, T., Saito, I., Yurimoto, T., Hara, S., Li, X. Y., Murakami, H., Kawase, Y., Sato, M., Inoue, Y., Ono, T., Fukazawa, K., Ishihara, K., Takai, M., & Ono, M. (2014). Design concept and elemental technologies of the helical flow total artificial heart. Transactions of Japanese Society for Medical and Biological Engineering, 52, OS-1-OS-2. https://doi.org/10.11239/jsmbe.52.OS-1

Abe, Y, Isoyama, T, Saito, I, Yurimoto, T, Hara, S, Li, XY, Murakami, H, Kawase, Y, Sato, M, Inoue, Y, Ono, T, Fukazawa, K, Ishihara, K, Takai, M & Ono, M 2014, 'Design concept and elemental technologies of the helical flow total artificial heart', Transactions of Japanese Society for Medical and Biological Engineering, vol. 52, pp. OS-1-OS-2. https://doi.org/10.11239/jsmbe.52.OS-1

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AU - Li, Xin Yang

AU - Murakami, Haruka

AU - Kawase, Yukino

AU - Sato, Masami

AU - Inoue, Yusuke

AU - Ono, Toshiya

AU - Fukazawa, Kyoko

AU - Ishihara, Kazuhiko

AU - Takai, Madoka

AU - Ono, Minoru

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Design concept and elemental technologies of the helical flow total artificial heart

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Keywords

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