Design and synthesis of RNA-binding fluorescent probes for analysis of small RNAs

Research output: Contribution to journalArticlepeer-review

Abstract

Although non-coding small RNAs were believed to be non-functional “junk” in the genome, recent studies have now highlighted their key roles in regulating gene expression in various biological processes. In this paper, we describe the current methods for analysis of microRNAs and small interfering RNAs (siRNAs), representatives of small RNAs, including our approaches based on RNA-binding fluorescent probes.

Original languageEnglish
Pages (from-to)531-540
Number of pages10
JournalBUNSEKI KAGAKU
Volume67
Issue number9
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • Affinity labeling
  • Fluorescent probes
  • Imaging
  • microRNAs
  • siRNAs

ASJC Scopus subject areas

  • Analytical Chemistry

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