Demonstration that spleen green hemeprotein is identical to granulocyte myeloperoxidase

M. Ikeda-Saito, H. C. Lee, K. Adachi, H. S. Eck, R. C. Prince, K. S. Booth, W. S. Caughey, S. Kimura

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

The biochemical, spectroscopic, enzymatic, and redox properties of spleen myeloperoxidase, a peroxidase formerly called 'spleen green hemeprotein', and granulocyte myeloperoxidase were compared by electrophoresis, amino-terminal amino acid sequences, optical and EPR spectroscopy, steady-state enzyme kinetics, and oxidation-reduction potential. The spleen enzyme exhibits properties indistinguishable from those of the granulocyte enzyme. We conclude that the spleen enzyme is indeed identical to granulocyte myeloperoxidase.

Original languageEnglish
Pages (from-to)4559-4563
Number of pages5
JournalJournal of Biological Chemistry
Volume264
Issue number8
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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