Delayed emergence of oseltamivir-resistant seasonal influenza A (H1N1) and pandemic influenza A(H1N1)pdm09 viruses in Myanmar

Clyde Dapat, Reiko Saito, Yadanar Kyaw, Yi Yi Myint, Htun Naing Oo, Khin Yi Oo, Makoto Naito, Go Hasegawa, Isolde C. Dapat, Hiroshi Suzuki

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The prevalence and timing of emergence of oseltamivir-resistant seasonal and pandemic influenza A (H1N1) viruses in Myanmar in 2008 and 2009 are described in this report. In 2008, the oseltamivir-resistant seasonal H1N1 virus was detected at a lower rate (6%) and emerged at least 2months later when compared with neighboring countries. Similarly, the prevalence of pandemic H1N1 virus was low (3%) and the timing of emergence was late (August 2009) in Myanmar. Interestingly, we detected three isolates that were resistant to both amantadine and oseltamivir. Limited movement of people into the country is attributed to the delayed emergence of drug-resistant seasonal and pandemic A(H1N1) viruses.

Original languageEnglish
Pages (from-to)766-771
Number of pages6
JournalInfluenza and other Respiratory Viruses
Volume7
Issue number5
DOIs
Publication statusPublished - 2013 Sep
Externally publishedYes

Keywords

  • Amantadine
  • Antiviral drug resistance
  • H1N1 subtype
  • Oseltamivir
  • Pandemic influenza
  • Seasonal influenza

ASJC Scopus subject areas

  • Epidemiology
  • Pulmonary and Respiratory Medicine
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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