Decreased cerebral glucose metabolism associated with mental deterioration in multi-infarct dementia

K. Meguro, C. Doi, M. Ueda, T. Yamaguchi, H. Matsui, S. Kinomura, M. Itoh, K. Yamada, H. Sasaki

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Cerebral glucose metabolism of 18 patients with multi-infarct dementia (MID) and 10 age-matched normal subjects were examined with positron emission tomography and the18-F-fluoro-deoxy-glucose technique. MID patients had significantly lower glucose metabolism in all the grey matter regions measured and were also characterized by more individuality in metabolic pattern. MID patients were also evaluated as to intelligence quotient (IQ). A positive correlation between IQ as shown by the Tanaka-Binet test and glucose metabolism for the entire grey matter was found. The clinical applicability of this test for predicting cerebral metabolism is discussed.

Original languageEnglish
Pages (from-to)305-309
Number of pages5
JournalNeuroradiology
Volume33
Issue number4
DOIs
Publication statusPublished - 1991 Jul

Keywords

  • Glucose metabolism
  • Intelligence quotient
  • Multi-infarct dementia
  • Positron emission tomography
  • Senile dementia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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