Decomposition of hydrogen peroxide by metmyoglobin: A cyclic formation of the ferryl intermediate

Genichi Tajima, Keiji Shikama

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

1. 1. Metmyoglobin reacted with H2O2 to form ferryl-myoglobin, which reverted back spontaneously to the met-form. 2. 2. Through this cyclic reaction of myoglobin between metMb(III) and ferryl-Mb(IV), we propose that H2O2, one of the potent oxidants in vivo, can be decomposed continuously in cardiac and skeletal muscle tissues in the absence of catalase and peroxidase.

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalInternational Journal of Biochemistry
Volume25
Issue number1
DOIs
Publication statusPublished - 1993 Jan 1

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Decomposition of hydrogen peroxide by metmyoglobin: A cyclic formation of the ferryl intermediate'. Together they form a unique fingerprint.

Cite this