DB-AT: A 2015 update to the Full-parasites database brings a multitude of new transcriptomic data for apicomplexan parasites

Marcin Jąkalski, Hiroyuki Wakaguri, Tabea G. Kischka, Yoshifumi Nishikawa, Shin Ichiro Kawazu, Makoto Matsubayashi, Fumiya Kawahara, Naotoshi Tsuji, Shinuo Cao, Fujiko Sunaga, Xuenan Xuan, Kazuhiro Okubo, Ikuo Igarashi, Josef Tuda, Arthur E. Mongan, Yuki Eshita, Ryuichiro Maeda, Wojciech Makałowski, Yutaka Suzuki, Junya Yamagishi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The previous release of our Full-parasites database (http://fullmal.hgc.jp/) brought enhanced functionality, an expanded full-length cDNA content, and new RNA-Seq datasets from several important apicomplexan parasites. The 2015 update witnesses the major shift in the databases content with focus on diverse transcriptomes of the apicomplexan parasites. The content of the database was substantially enriched with transcriptome information for new apicomplexan parasites. The latest version covers a total of 17 species, with addition of our newly generated RNA-Seq data of a total of 909 150 388 tags. Moreover, we have generated and included two novel and unique datasets, which represent diverse nature of transcriptomes in individual parasites in vivo and in vitro. One is the data collected from 116 Indonesian patients infected with Plasmodium falciparum. The other is a series of transcriptome data collected from a total of 38 single cells of P. falciparum cultured in vitro. We believe that with the recent advances our database becomes an even better resource and a unique platform in the analysis of apicomplexan parasites and their interaction with their hosts. To adequately reflect the recent modifications and the current content we have changed the database name to DB-AT - DataBase of Apicomplexa Transcriptomes.

Original languageEnglish
Pages (from-to)D631-D636
JournalNucleic Acids Research
Volume43
Issue numberD1
DOIs
Publication statusPublished - 2015 Jan 15

ASJC Scopus subject areas

  • Genetics

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    Jąkalski, M., Wakaguri, H., Kischka, T. G., Nishikawa, Y., Kawazu, S. I., Matsubayashi, M., Kawahara, F., Tsuji, N., Cao, S., Sunaga, F., Xuan, X., Okubo, K., Igarashi, I., Tuda, J., Mongan, A. E., Eshita, Y., Maeda, R., Makałowski, W., Suzuki, Y., & Yamagishi, J. (2015). DB-AT: A 2015 update to the Full-parasites database brings a multitude of new transcriptomic data for apicomplexan parasites. Nucleic Acids Research, 43(D1), D631-D636. https://doi.org/10.1093/nar/gku1240