Cytogenetic abnormality 46,XX,add(21)(q11.2) in a patient with follicular dendritic cell sarcoma

Naomi Suzuki, Hiroki Katsusihma, Kengo Takeuchi, Shigeo Nakamura, Kenichi Ishizawa, Seiichi Ishii, Takuya Moriya, John F. DeCoteau, Ikuo Miura, Ryo Ichinohasama

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The case of a patient with follicular dendritic cell (FDC) sarcoma with chromosomal aberration add(21)(q11.2) is described. Cytogenetic studies showed the karyotype 46,XX,add(21)(q11.2)[3]/46,XX[17], although the encoded protein involved was not clarified. The abnormal pattern was quite simple, and different from a previous report. The clinical course of the FDC sarcoma in this case has been indolent, as for most FDC sarcoma patients. Although this patient suffered from breast carcinoma 6 years after the onset of FDC sarcoma, the carcinoma showed different histological and phenotypic profiles.

Original languageEnglish
Pages (from-to)54-57
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume186
Issue number1
DOIs
Publication statusPublished - 2008 Oct 1

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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