Cytofluorometric Analysis of Nuclear DNA and Cell Protein in Pancreatic Carcinoma

Hidemi Yamauchi, Kenji Kakizaki, Yasuo Yamada, Ryo Ichinohasama, Noboru Tanaka

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Yamauchi, H., Ichinohasama, R., Kakizaki, K., Yamada, Y. and Tanaka, N. Cytofluorometric Analysis of Nuclear DNA and Cell Protein in Pancreatic Carcinoma. Tohoku J. Exp. Med., 1989, 159 (3), 245-246-Cytofluorometric analysis of pancreatic carcinoma was performed in six patients, using a method for simultaneous one-step staining of nuclear DNA and cell protein. All carcinoma cells demonstrated ploidy abnormalities in DNA histogram; polyploid with or without aneuploidization. The carcinoma cells of two patients who died within one year after resection showed significantly higher polyploidization of DNA and bigger amount of cell protein than those of four patients who survived longer than one year after surgical managements.

Original languageEnglish
Pages (from-to)245-246
Number of pages2
Journalthe tohoku journal of experimental medicine
Volume159
Issue number3
DOIs
Publication statusPublished - 1989

Keywords

  • DNA ploidy pattern
  • cell protein
  • pancreatic carcinoma
  • prognosis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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