Abstract
A cyclic dipeptide based chiral ligand, cyclo[-His(Tr)-His(Tr)-] (Tr = triphenylmethyl), was designed and prepared through bis-(τ)-tritylation of two imidazole rings of cyclo[-His-His-]. The complex prepared in situ by mixing Cu(OTf)2 with equimolar amount of this ligand successfully catalyzed asymmetric Diels-Alder reactions in fair to good yields and moderate selectivities.
Original language | English |
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Pages (from-to) | 1171-1176 |
Number of pages | 6 |
Journal | Heterocycles |
Volume | 78 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2009 May 1 |
Keywords
- Bidentate Ligand
- Cu-Gatalyzed Reaction
- Cyclic Dipeptide
- Enantioselectivity
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry