Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

Takashi Takahashi, Takayuki Doi, Makoto Nakazawa, Haruo Yamada

Research output: Contribution to journalArticlepeer-review

Abstract

We report here the synthesis of a chiral A-ring synthon for la, 25-dihydroxyvitamin D3 starting from d-mannitol by using the cyanohydrin cyclization methodology.

Original languageEnglish
Pages (from-to)299-304
Number of pages6
JournalNatural Product Letters
Volume1
Issue number4
DOIs
Publication statusPublished - 1993 Feb 1
Externally publishedYes

Keywords

  • 25-dihydroxyvitamin D3
  • A-ring synthon
  • cyanohydrin alkylation
  • d-mannitol

ASJC Scopus subject areas

  • Molecular Medicine

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