Cutting-edge information for the management of acute pancreatitis

Tadahiro Takada, Koichi Hirata, Toshihiko Mayumi, Masahiro Yoshida, Miho Sekimoto, Masahiko Hirota, Yasutoshi Kimura, Kazunori Takeda, Shuji Isaji, Keita Wada, Hodaka Amano, Toshifumi Gabata, Shinjyu Arata, Morihisa Hirota, Masamichi Yokoe, Seiki Kiriyama, Takeo Nakayama, Kuni Otomo, Masao Tanaka, Tooru Shimosegawa

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Considering that the Japanese (JPN) guidelines for the management of acute pancreatitis were published in Takada et al. (J HepatoBiliary Pancreat Surg 13:2-6, 2006), doubts will be cast as to the reason for publishing a revised edition of the Guidelines for the management of acute pancreatitis: the JPN guidelines 2010, at this time. The rationale for this is that new criteria for the severity assessment of acute pancreatitis were made public on the basis of a summary of activities and reports of shared studies that were conducted in 2008. The new severity classification is entirely different from that adopted in the 2006 guidelines. A drastic revision was made in the new criteria. For example, about half of the cases that have been assessed previously as being 'severe' are assessed as being 'mild' in the new criteria. The JPN guidelines 2010 are published so that consistency between the criteria for severity assessment in the first edition and the new criteria will be maintained. In the new criteria, severity assessment can be made only by calculating the 9 scored prognostic factors. Severity assessment according to the contrast-enhanced computed tomography (CT) grade was made by scoring the poorly visualized pancreatic area in addition to determining the degree of extrapancreatic progress of inflammation and its extent. Changes made in accordance with the new criteria are seen in various parts of the guidelines. In the present revised edition, postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is treated as an independent item. Furthermore, clinical indicators (pancreatitis bundles) are presented to improve the quality of the management of acute pancreatitis and to increase adherence to new guidelines.

Original languageEnglish
Pages (from-to)3-12
Number of pages10
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Issue number1
Publication statusPublished - 2010 Jan
Externally publishedYes


  • Acute pancreatitis
  • Gallstone-induced pancreatitis
  • Guidelines
  • Pancreatitis bundle
  • Post-ERCP pancreatitis

ASJC Scopus subject areas

  • Surgery
  • Hepatology


Dive into the research topics of 'Cutting-edge information for the management of acute pancreatitis'. Together they form a unique fingerprint.

Cite this