Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor

Biochemistry, Genetics and Molecular Biology

• DNA Damage Response 60%
• Poly ADP Ribose Polymerase 50%
• Homologous Recombination 40%
• DNA Damage Checkpoint 30%
• BRCA1 20%
• Non-Homologous End Joining 20%
• Sensitization 20%
• Clinical Study 20%
• Histone Acetyltransferase 20%
• Histone Acetylation 20%
• Nested Gene 10%
• Promoter Region 10%
• Electric Potential 10%
• Cancer Cell 10%
• Apoptosis 10%
• Protein Kinase 10%
• Ku70 10%
• Ku80 10%
• IC50 10%
• Turmeric 10%
• Chemosensitization 10%
• Mitotic Catastrophe 10%
• Curcuma 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Curcumin 100%
• DNA 90%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase Inhibitor 40%
• ATR Protein 30%
• Histone 20%
• Malignant Neoplasm 20%
• Histone Acetyltransferase 20%
• Anticarcinogen 10%
• IC50 10%
• Combination Therapy 10%
• Protein Kinase 10%
• Neoplasm 10%
• Double Stranded DNA 10%
• Curcuma Longa 10%
• Turmeric 10%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 10%
• Apoptosis 10%

Neuroscience

• Curcumin 100%
• DNA Damage Response 60%
• Poly ADP Ribose Polymerase 50%
• Homologous Recombination 40%
• ATR Protein 30%
• Histone Acetyltransferase 20%
• Non-Homologous End Joining 20%
• Histone Acetylation 20%
• Apoptosis 10%
• Protein Kinases 10%
• In Vitro 10%
• Promoter Region 10%
• Double Stranded DNA 10%
• Gene 10%
• Turmeric 10%
• Mitotic Catastrophe 10%