Cu-Catalyzed switchable synthesis of functionalized pyridines and pyrroles

Zheng Ling, Fang Xie, Ilya D. Gridnev, Masahiro Terada, Wanbin Zhang

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Herein, we describe a high yielding and switchable synthesis of a range of functionalized pyridines and pyrroles via Cu-catalyzed cascade reactions with alkynes and N-sulfonyl azadienes which are readily available from saccharin. Both unsymmetrical 2,4,6-trisubstituted pyridines and multi-substituted pyrroles could be transformed into some bioactive compounds and chiral ligands.

Original languageEnglish
Pages (from-to)9446-9449
Number of pages4
JournalChemical Communications
Volume54
Issue number68
DOIs
Publication statusPublished - 2018

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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