Crystallographic approach to regenerated and pathological hard tissues

Takayoshi Nakano, Takuya Ishimoto, Jee Wook Lee, Yukichi Umakoshi, Masaya Yamamoto, Yasuhiko Tabata, Akio Kobayashi, Hiroyoshi Iwaki, Kunio Takaoka, Mariko Kawai, Toshio Yamamoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

A dominant inorganic substance in hard tissue is known to be a biological apatite (BAp) nano-crystal which basically crystallizes in an anisotropic hep lattice, and the BAp c-axis is parallel to extended collagen fibrils. We applied the microbeam X-ray diffractometer system with an incident beam spot 100μm or 50μm in diameter to the original, regenerated and pathological hard tissues in order to analyze the preferential alignment of the BAp c-axis as a parameter of bone quality closely relating to the mechanical function. We conclude that the BAp orientational distribution in the hard tissues is a new measure to evaluate stress distribution in vivo, nano-scale microstructure and the related mechanical function, healing process of the regenerated bone and progress of the bone diseases.

Original languageEnglish
Title of host publicationAdvanced Structural and Functional Materials Design - Proceedings of the International Symposium on Advanced Structural and Functional Materials Design, 2004
PublisherTrans Tech Publications Ltd
Pages255-260
Number of pages6
ISBN (Print)0878499962, 9780878499960
DOIs
Publication statusPublished - 2006
Externally publishedYes
EventInternational Symposium on Advanced Structural and Functional Materials Design, 2004 - Osaka, Japan
Duration: 2004 Nov 102004 Nov 12

Publication series

NameMaterials Science Forum
Volume512
ISSN (Print)0255-5476
ISSN (Electronic)1662-9752

Other

OtherInternational Symposium on Advanced Structural and Functional Materials Design, 2004
CountryJapan
CityOsaka
Period04/11/1004/11/12

Keywords

  • Biological apatite
  • Bone
  • Bone regeneration
  • Crystal orientation
  • Microbeam X-ray diffraction
  • Osteoarthritis
  • Osteopetrosis
  • Osteoporosis
  • Pathological hard tissue
  • Tissue engineering
  • rBMP-2

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Nakano, T., Ishimoto, T., Lee, J. W., Umakoshi, Y., Yamamoto, M., Tabata, Y., Kobayashi, A., Iwaki, H., Takaoka, K., Kawai, M., & Yamamoto, T. (2006). Crystallographic approach to regenerated and pathological hard tissues. In Advanced Structural and Functional Materials Design - Proceedings of the International Symposium on Advanced Structural and Functional Materials Design, 2004 (pp. 255-260). (Materials Science Forum; Vol. 512). Trans Tech Publications Ltd. https://doi.org/10.4028/0-87849-996-2.255