TY - JOUR
T1 - Correlations between extent of X-ray infiltration and levels of serum C-reactive protein in adult non-severe community-acquired pneumonia
AU - Tamayose, Maki
AU - Fujita, Jiro
AU - Parrott, Gretchen
AU - Miyagi, Kazuya
AU - Maeshiro, Tatsuji
AU - Hirata, Tetsuo
AU - Higa, Futoshi
AU - Tateyama, Masao
AU - Watanabe, Akira
AU - Aoki, Nobuki
AU - Niki, Yoshihito
AU - Kadota, Jun ichi
AU - Yanagihara, Katsunori
AU - Kaku, Mitsuo
AU - Hori, Seiji
AU - Kohno, Shigeru
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Pneumonia cases can vary in both severity and chest X-ray findings. Elevated C-reactive protein (CRP) levels may be an indicator of disease severity. We retrospectively evaluated factors correlated with the extent of chest X-ray infiltration both in community-acquired pneumonia (CAP) and a subgroup of cases with pneumococcal pneumonia. In a clinical study that evaluated the efficacy of sitafloxacin, 137 patients with CAP had been previously enrolled. In our study, 75 patients with pneumococcal pneumonia were identified among these 137 CAP patients. The extent of chest X-ray infiltration was scored and correlations with age, sex, body temperature, white blood cell (WBC) count, and CRP levels were analyzed using multivariate analysis with logistic regression. Significant correlations were observed between the extent of chest X-ray infiltration and CRP levels in both CAP and pneumococcal pneumonia. Our data indicates that CRP is a valuable and informative resource that could reflect the severity of pneumonia in cases of both CAP and pneumococcal pneumonia.
AB - Pneumonia cases can vary in both severity and chest X-ray findings. Elevated C-reactive protein (CRP) levels may be an indicator of disease severity. We retrospectively evaluated factors correlated with the extent of chest X-ray infiltration both in community-acquired pneumonia (CAP) and a subgroup of cases with pneumococcal pneumonia. In a clinical study that evaluated the efficacy of sitafloxacin, 137 patients with CAP had been previously enrolled. In our study, 75 patients with pneumococcal pneumonia were identified among these 137 CAP patients. The extent of chest X-ray infiltration was scored and correlations with age, sex, body temperature, white blood cell (WBC) count, and CRP levels were analyzed using multivariate analysis with logistic regression. Significant correlations were observed between the extent of chest X-ray infiltration and CRP levels in both CAP and pneumococcal pneumonia. Our data indicates that CRP is a valuable and informative resource that could reflect the severity of pneumonia in cases of both CAP and pneumococcal pneumonia.
KW - C-reactive protein
KW - Chest X-ray infiltration
KW - Community-acquired pneumonia
KW - Streptococcus pneumoniae
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UR - http://www.scopus.com/inward/citedby.url?scp=84939947612&partnerID=8YFLogxK
U2 - 10.1016/j.jiac.2015.02.009
DO - 10.1016/j.jiac.2015.02.009
M3 - Article
C2 - 25817351
AN - SCOPUS:84939947612
VL - 21
SP - 456
EP - 463
JO - Journal of Infection and Chemotherapy
JF - Journal of Infection and Chemotherapy
SN - 1341-321X
IS - 6
ER -
