TY - GEN
T1 - Correlation of extract composition on antioxidant activity of electrospun polyvinylpyrrolidone/bassela rubra linn leaf extract composite
AU - Septiani, Eka Lutfi
AU - Gabriel, Azmi Alvian
AU - Prastuti, Okky Putri
AU - Indahsari, Defi Nur
AU - Ariyanti, Ervina Diah
AU - Machmudah, Siti
AU - Winardi, Sugeng
AU - Wahyudiono,
AU - Kanda, Hideki
AU - Goto, Motonobu
N1 - Funding Information:
The author gratefully thanks DIKTI which supported the grant of this research.
Publisher Copyright:
© 2020 Trans Tech Publications Ltd, Switzerland.
PY - 2020
Y1 - 2020
N2 - Nanofiber through electrospinning process has been developed as a promising material for wound dressing due to its large porosity and high surface area. This characteristic of nanofiber provides an adequate gas permeability surrounding the wound which prevents the healing failure. The best wound dressing not only maintain a wound to have a good gas permeability but also to have an active agent giving an antibacterial and antiinflammation property. This research aims to combine a synthetic polymer and active agent, polyvinylpyrrolidone (PVP) and Bassela rubra linn leaf extract (BRLE), become nanofibrous material. The electrospinning process was conducted in two steps. The first step is to obtain the best voltage of PVP electrospinning by using the voltage of 10, 12, 15, 17 kV. The other step is combining PVP to 2%, 5%, 8% of BRLE. The first step shows the best operation condition is using 12 kV. Hence, it is used to obtain nanofiber with different BRLE percentage. Based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the result indicates that increase the BRLE composition will rise the antioxidant activity because of the smaller diameter size.
AB - Nanofiber through electrospinning process has been developed as a promising material for wound dressing due to its large porosity and high surface area. This characteristic of nanofiber provides an adequate gas permeability surrounding the wound which prevents the healing failure. The best wound dressing not only maintain a wound to have a good gas permeability but also to have an active agent giving an antibacterial and antiinflammation property. This research aims to combine a synthetic polymer and active agent, polyvinylpyrrolidone (PVP) and Bassela rubra linn leaf extract (BRLE), become nanofibrous material. The electrospinning process was conducted in two steps. The first step is to obtain the best voltage of PVP electrospinning by using the voltage of 10, 12, 15, 17 kV. The other step is combining PVP to 2%, 5%, 8% of BRLE. The first step shows the best operation condition is using 12 kV. Hence, it is used to obtain nanofiber with different BRLE percentage. Based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the result indicates that increase the BRLE composition will rise the antioxidant activity because of the smaller diameter size.
KW - Antioxidant activity
KW - Basella rubra linn (binahong) extract
KW - Electrospinning
KW - Nanofiber
UR - http://www.scopus.com/inward/record.url?scp=85088305701&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85088305701&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.851.122
DO - 10.4028/www.scientific.net/KEM.851.122
M3 - Conference contribution
AN - SCOPUS:85088305701
SN - 9783035716276
T3 - Key Engineering Materials
SP - 122
EP - 127
BT - Advanced Materials for Renewable Energy
A2 - Aripriharta, Aripriharta
A2 - Aripriharta, Aripriharta
A2 - Puspitasari, Poppy
A2 - Puspitasari, Poppy
PB - Trans Tech Publications Ltd
T2 - Annual International Conference on Renewable Energy, ICORE 2019
Y2 - 9 August 2019 through 10 August 2019
ER -