Correlation between visual field defect and retinal nerve fiber layer thickness in glaucoma

Takaaki Otomo, Nobuo Fuse, Motohiko Seimiya, Toru Nakazawa, Kohji Nishida

Research output: Contribution to journalArticle

Abstract

Purpose: To report the correlation between visual field defect and retinal nerve fiber layer thickness (RNFLT) in glaucoma. Cases: This study was made on 120 eyes of 62 patients who were diagnosed with primary open-angle glaucoma in its broader sense. The series comprised 62 male and 58 female eyes. The age averaged 50.2 ± 18.1 years. RNFLT was measured by optical coherence tomography (OCT3000). Visual field was evaluated by mean deviation (MD) and pattern standard deviation (PSD) of Humphrey automated perimeter. Results: RNFLT showed a significant correlation with MD (r=0.717, p=0.000) and PSD (r= - 0.566, p=0.000). When glaucoma was classified into 3 groups according to MD value, correlation between RNFLT and MD was present only in early and advanced stages and was absent in medium stage. Conclusion: RNFLT in glaucoma is significantly correlated with visual field defect. This correlation may be less apparent in moderately advanced glaucoma.

Original languageEnglish
Pages (from-to)723-726
Number of pages4
JournalJapanese Journal of Clinical Ophthalmology
Volume62
Issue number5
Publication statusPublished - 2008 Jun 10

ASJC Scopus subject areas

  • Ophthalmology

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