Correlated responses of respiratory disease and immune capacity traits of Landrace pigs selected for Mycoplasmal pneumonia of swine (MPS) lesion

Toshihiro Okamura, Kouki Maeda, Wataru Onodera, Hiroshi Kadowaki, Chihiro Kojima-Shibata, Eisaku Suzuki, Hirohide Uenishi, Masahiro Satoh, Keiichi Suzuki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Five generations of Landrace pigs selected for average daily gain, backfat thickness, Mycoplasmal pneumonia of swine (MPS) lesion score, and plasma cortisol levels, was executed to decrease the MPS lesion score. Genetic parameters and correlated genetic responses for respiratory disease and peripheral blood immune traits were estimated in 1395 Landrace pigs. We estimated the negative genetic correlation of MPS lesion score with phagocytic activity (PA) at 7 weeks of age (-0.67). The breeding values of PA at 7 weeks of age and 105 kg body weight and the correlated selection response of the ratio of granular leukocytes to lymphocytes at 105 kg body weight were significantly increased, and sheep red blood cell-specific antibody production (AP) was significantly decreased in a selection-dependent manner. Increasing of natural immunological indicators (e.g. PA) and decreasing of humoral immunological indicator (e.g. AP) were observed due to genetically decreasing MPS lesion score.

Original languageEnglish
Pages (from-to)1099-1105
Number of pages7
JournalAnimal science journal = Nihon chikusan Gakkaiho
Volume87
Issue number9
DOIs
Publication statusPublished - 2016 Sep 1

Keywords

  • genetic parameter
  • genetic trend
  • immunity
  • pig
  • respiratory disease

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Fingerprint Dive into the research topics of 'Correlated responses of respiratory disease and immune capacity traits of Landrace pigs selected for Mycoplasmal pneumonia of swine (MPS) lesion'. Together they form a unique fingerprint.

Cite this