Correlated inhibitory firing and spike-timing-dependent plasticity

Ichiro Sakurai; Shigeru Kubota; Michio Niwano

doi:10.1007/978-3-642-42054-2_21

Correlated inhibitory firing and spike-timing-dependent plasticity

Ichiro Sakurai, Shigeru Kubota, Michio Niwano

Human Information Systems Division

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Cortical inhibition by γ-aminobutyric acid (GABA) has been widely suggested to be required to trigger ocular dominance (OD) plasticity in the visual cortex. However, there is also evidence that only the circuits mediated by specific GABA_A receptors can induce OD plasticity, which implies the importance of localized GABA circuits in this process. In this study, to investigate the role of local inhibition in visual plasticity, we simulated the synaptic dynamics regulated by lateral and backward inhibition. The lateral inhibition facilitated competitive interactions between different groups of excitatory correlated inputs, which were required to elicit experience-dependent synaptic modifications. Conversely, the backward inhibition suppressed such competitive interactions, which prevented synapses from reflecting past sensory experience. Our results suggest that the interactions between lateral and backward inhibition may regulate the timing and level of cortical plasticity by modulating the activity-dependent competitive function.

Original language	English
Title of host publication	Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings
Pages	161-167
Number of pages	7
Edition	PART 1
DOIs	https://doi.org/10.1007/978-3-642-42054-2_21
Publication status	Published - 2013
Event	20th International Conference on Neural Information Processing, ICONIP 2013 - Daegu, Korea, Republic of Duration: 2013 Nov 3 → 2013 Nov 7

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Number	PART 1
Volume	8226 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	20th International Conference on Neural Information Processing, ICONIP 2013
Country	Korea, Republic of
City	Daegu
Period	13/11/3 → 13/11/7

Keywords

Firing correlation
Gaba inhibition
STDP
Synaptic competition
Visual cortex

ASJC Scopus subject areas

Theoretical Computer Science
Computer Science(all)

Access to Document

10.1007/978-3-642-42054-2_21

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Sakurai, I., Kubota, S., & Niwano, M. (2013). Correlated inhibitory firing and spike-timing-dependent plasticity. In Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings (PART 1 ed., pp. 161-167). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 8226 LNCS, No. PART 1). https://doi.org/10.1007/978-3-642-42054-2_21

Correlated inhibitory firing and spike-timing-dependent plasticity. / Sakurai, Ichiro; Kubota, Shigeru; Niwano, Michio.

Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings. PART 1. ed. 2013. p. 161-167 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 8226 LNCS, No. PART 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Sakurai, I, Kubota, S & Niwano, M 2013, Correlated inhibitory firing and spike-timing-dependent plasticity. in Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings. PART 1 edn, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 1, vol. 8226 LNCS, pp. 161-167, 20th International Conference on Neural Information Processing, ICONIP 2013, Daegu, Korea, Republic of, 13/11/3. https://doi.org/10.1007/978-3-642-42054-2_21

Sakurai I, Kubota S, Niwano M. Correlated inhibitory firing and spike-timing-dependent plasticity. In Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings. PART 1 ed. 2013. p. 161-167. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 1). https://doi.org/10.1007/978-3-642-42054-2_21

Sakurai, Ichiro ; Kubota, Shigeru ; Niwano, Michio. / Correlated inhibitory firing and spike-timing-dependent plasticity. Neural Information Processing - 20th International Conference, ICONIP 2013, Proceedings. PART 1. ed. 2013. pp. 161-167 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 1).

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