The original version of our manuscript, entitled, “ The IL1RN mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation” unfortunately contained mistakes in Fig. 1a and d legends. The text should read as follows: a. Immunoblot analysis with an anti-FLAG antibody of HEK- 293 T cells transfected with insert-free FLAG-tagged vector (mock) or with expression vectors carrying various IL1RN alleles:WT, R29X, or R29X-M38A (methionine 38 to alanine mutation, blocking reinitiation of translation at M38) or E57X. d. Protein structure model of IL-1Ra and IL-1R1. IL-1Ra (blue) was superimposed on EBI-005 in complex with IL-1R1 (green).
ASJC Scopus subject areas
- Immunology and Allergy