Correct diagnosis of vascular encasement and longitudinal extension of hilar cholangiocarcinoma by four-channel multidetector-row computed tomography

Tadayuki Okumoto, Akihiro Sato, Takayuki Yamada, Kei Takase, Toshio Matsuhashi, Masashi Tsuda, Kazumasa Seiji, Tadashi Ishibashi, Shuichi Higano, Yu Katayose, Michiaki Unno, Shoki Takahashi

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Accurate diagnosis of local invasion of hilar cholangiocarcinomas is challenging due to their small size and the anatomic complexity of the hepatic hilar region. On the other hand, the correct diagnosis of local invasion is essential for assuring the possibility of curative surgery. The purpose of this study was to evaluate the feasibility of four-channel multidetoctor-row computed tomography (MDCT) in the assessment of vascular and bile duct involvement, by which we could obtain useful information for the surgical management of hilar cholangiocarcinoma. The subjects were 18 patients for whomlhe extent of tumor invasion was surgically and pathologically confirmed, All patients underwent preoperative multiphasic CT scanning by MDCT. Arterial and portal dominant phases were acquired using a detector configuration of 1.25 mm × 4 mm, and both axial and multiplanar reconstructed images were interpreted. Longitud1nal extension was evaluated up to second-order branches. Vascular invasion is considered to be the degree of tumor contiguity to the hepatic arteries and portal vein and was graded by CT. The longitudinal extension was correctly diagnosed in 14 patients (77.8%). Hepatic artery invasion was correctly. diagnosed in 17 patients with sensitivity of 100% and specificity of 90%, respectively. Portal vein invasion was correctly diagnosed in 47 of 51 branches with sensitivity and specificity of 92.3% and 90.2%, respectively. Multiplanar reconstructed images contributed to the correct diagnosis for both vascular encasement and longitudinal tumor extension. In conclusion, MDCT is useful in preoperative evaluation of hilar choiangiocarcinoma, especially when combined with multiplanar reconstructed images.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalTohoku Journal of Experimental Medicine
Volume217
Issue number1
DOIs
Publication statusPublished - 2009

Keywords

  • Diagnostic radiology
  • Hilar cholangiocarcinoma
  • Multidetector-row computed tomography
  • Multiplanar reconstruction
  • Preoperative evaluation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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