Coronary artery spasm and perivascular adipose tissue inflammation: Insights from translational imaging research

Kazuma Ohyama, Yasuharu Matsumoto, Hiroaki Shimokawa

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Perivascular adipose tissue, which constitutes perivascular components along with the adventitial vasa vasorum, plays an important role as a source of various inflammatory mediators in cardiovascular disease. Inflammatory changes in the coronary adventitia are thought to be involved in the pathogenesis of coronary artery spasm and vasospastic angina. Recent advances in translational research using noninvasive imaging modalities, including 18F-fluorodeoxyglucose PET and cardiac CT, have enabled us to visualise perivascular inflammation in the pathogenesis of coronary artery spasm. These modality approaches appear to be clinically useful as a non-invasive tool for examining the presence and severity of vasospastic angina.

Original languageEnglish
Pages (from-to)6-9
Number of pages4
JournalEuropean Cardiology Review
Volume14
Issue number1
DOIs
Publication statusPublished - 2019

Keywords

  • 18F-fluorodeoxyglucose PET
  • Cardiac CT
  • Coronary adventitia
  • Coronary spasm
  • Perivascular adipose tissue

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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