@article{5b995662e8094fa199e327c9d2bd6263,
title = "Coronary artery spasm and perivascular adipose tissue inflammation: Insights from translational imaging research",
abstract = "Perivascular adipose tissue, which constitutes perivascular components along with the adventitial vasa vasorum, plays an important role as a source of various inflammatory mediators in cardiovascular disease. Inflammatory changes in the coronary adventitia are thought to be involved in the pathogenesis of coronary artery spasm and vasospastic angina. Recent advances in translational research using noninvasive imaging modalities, including 18F-fluorodeoxyglucose PET and cardiac CT, have enabled us to visualise perivascular inflammation in the pathogenesis of coronary artery spasm. These modality approaches appear to be clinically useful as a non-invasive tool for examining the presence and severity of vasospastic angina.",
keywords = "18F-fluorodeoxyglucose PET, Cardiac CT, Coronary adventitia, Coronary spasm, Perivascular adipose tissue",
author = "Kazuma Ohyama and Yasuharu Matsumoto and Hiroaki Shimokawa",
note = "Funding Information: Disclosure: This work was supported in part by Grants-in-Aid for Scientific Research (18890018, 16K19384) and the Global COE Project (F02); Grants-in-Aid (H22-Shinkin-004) from the Japanese Ministry of Education, Culture, Sports, Science and Technology, Tokyo, Japan; the grant for young investigators of translational research from Tohoku University Hospital; and Grants-in-Aid for Scientific Research (16K19384). Received: 7 January 2019 Accepted: 6 February 2019 Citation: European Cardiology Review 2019;14(1):6–9. DOI: https://doi.org/10.15420/ecr.2019.3.2 Correspondence: Hiroaki Shimokawa, Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan. E: shimo@cardio.med.tohoku.ac.jp Open Access: This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.",
year = "2019",
doi = "10.15420/ecr.2019.3.2",
language = "English",
volume = "14",
pages = "6--9",
journal = "European Cardiology",
issn = "1758-3756",
publisher = "Radcliffe Publishing Ltd.",
number = "1",
}