Co‐production of Interleukin‐1 and Interleukin‐6 in Tumor Cell Lines Elaborating Colony‐stimulating Factors

Yoshiaki Okuno, Takayuki Takahashi, Akira Suzuki, Manabu Fukumoto, Kishiko Nakamura, Hiroo Imura

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Six carcinoma cell lines elaborating colony‐stimulating factors (CSFs) were examined by enzyme‐linked immtmosorbent assay and Northern blotting to determine whether or not they co‐produced interleukin‐lα (IL‐lα), IL‐lβ and IL‐6. All 6 cell lines were co‐producers; IL‐lα was produced in all 6, IL‐6 in 5 and IL‐1β in 3 of them. These results indicate that IL‐1 and IL‐6 are commonly co‐produced in CSF‐producing tumors.

Original languageEnglish
Pages (from-to)890-892
Number of pages3
JournalJapanese Journal of Cancer Research
Volume82
Issue number8
DOIs
Publication statusPublished - 1991 Aug
Externally publishedYes

Keywords

  • Colony
  • Interleukin‐1
  • Interleukin‐6
  • producing cell line
  • stimulating factor

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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