Copper-mediated aromatic amination reaction and its application to the total synthesis of natural products

Kentaro Okano, Hidetoshi Tokuyama, Tohru Fukuyama

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)

Abstract

Herein, we review copper-mediated aromatic amination reactions including the classical Ullmann coupling and the recently developed mild aryl amination with an effective ligand as well as the C-H amination reaction. Several applications of intramolecular aryl amination to the syntheses of natural products demonstrate the general applicability of the reaction.

Original languageEnglish
Pages (from-to)13650-13663
Number of pages14
JournalChemical Communications
Volume50
Issue number89
DOIs
Publication statusPublished - 2014 Oct 14

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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