The [3+2] cycloaddition of nonactivated terminal alkynes and trimethylsilyl azide proceeded smoothly in the presence of CuI catalyst and DMF/MeOH, to give the corresponding N-unsubstituted triazoles in good to high yields. The reaction most probably proceeds through the in situ formation of a copper acetylide species and hydrazoic acid, followed by a successive [3+2] cycloaddition reaction.
|Number of pages||3|
|Journal||European Journal of Organic Chemistry|
|Publication status||Published - 2004 Sept 13|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry