TY - JOUR
T1 - Copper-Catalyzed sp3 C-H Aminative Cyclization of 2-Alkyl-N-arylbenzamides
T2 - An Approach for the Synthesis of N-Aryl-isoindolinones
AU - Nozawa-Kumada, Kanako
AU - Kadokawa, Jun
AU - Kameyama, Takehiro
AU - Kondo, Yoshinori
PY - 2015/9/18
Y1 - 2015/9/18
N2 - The synthesis of isoindolinones via copper-catalyzed sp3 C-H functionalization of 2-alkyl-N-substituted benzamides is described. This process does not require the preparation of halogenated substitutes, expensive transition metals, or toxic Sn or CO gas. This method provides an efficient approach to generate various functionalized isoindolinones.
AB - The synthesis of isoindolinones via copper-catalyzed sp3 C-H functionalization of 2-alkyl-N-substituted benzamides is described. This process does not require the preparation of halogenated substitutes, expensive transition metals, or toxic Sn or CO gas. This method provides an efficient approach to generate various functionalized isoindolinones.
UR - http://www.scopus.com/inward/record.url?scp=84941904377&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941904377&partnerID=8YFLogxK
U2 - 10.1021/acs.orglett.5b02235
DO - 10.1021/acs.orglett.5b02235
M3 - Article
AN - SCOPUS:84941904377
VL - 17
SP - 4479
EP - 4481
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 18
ER -