Conversion of vindoline into 11-mesyloxytabersonine

Yuki Han-Ya, Tomohiko Inui, Satoshi Yokoshima, Hidetoshi Tokuyama, Tohru Fukuyama

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Conversion of readily available vindoline to 11-mesyloxytabersonine, a versatile synthetic intermediate for indole alkaloids, has been achieved by a 9-step sequence in 39% overall yield.

Original languageEnglish
Pages (from-to)800-804
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume64
Issue number7
DOIs
Publication statusPublished - 2016

Keywords

  • Alkaloid
  • Indole
  • Natural product
  • Tabersonine
  • Vindoline

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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