Abstract
The cyclization reaction of various 2-ethynylanilines, which were easily synthesized from 2-haloanilines by the palladium-catalyzed reaction with terminal alkynes, with tetrabutylammonium fluoride (TBAF) to yield 2-substituted indoles proceeded at refluxing or room temperature in THF in excellent yields without affecting the bromo, chloro, cyano, ethoxycarbonyl, and ethynyl groups.
Original language | English |
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Pages (from-to) | 529-534 |
Number of pages | 6 |
Journal | Journal of the Chemical Society - Perkin Transactions 1 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1999 Jan 1 |
ASJC Scopus subject areas
- Chemistry(all)