Convenient route to derivatives of the 2-deoxysugar subunits of the Kedarcidin chromophore: L-mycarose and L-kedarosamine

Martin J. Lear, Masahiro Hirama

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

An efficient and practical synthesis of mycarose and kedarosamine derivatives has been devised from ethyl (S)-lactate via a versatile (E)- alkene intermediate. Noteworthy transformations include a highly trans- selective one-pot Julia olefination protocol and intramolecular cyclisation of a 2,3-epoxy carbamate.

Original languageEnglish
Pages (from-to)4897-4900
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number26
DOIs
Publication statusPublished - 1999 Jun 25

Keywords

  • Amino sugars
  • Cyclisation
  • Glycosides
  • Olefination

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Convenient route to derivatives of the 2-deoxysugar subunits of the Kedarcidin chromophore: L-mycarose and L-kedarosamine'. Together they form a unique fingerprint.

  • Cite this