Control of wall thickness of blood vessel biomodel made of poly (vinyl alcohol) hydrogel by a three-dimensional-rotating spin dip-coating method

Hiroyuki Kosukegawa, Chihaya Kiyomitsu, Makoto Ohta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

To control the thickness of a PVA-H biomodel of human arteries and veins (150 to 800 μm in thickness), a threedimensional-rotating spin dip-coating apparatus was fabricated. A straight aluminum cylinder (Ra = 0.16 μm) was employed as substrate. Spin dip-coating was carried out in a cooling chamber at 10°C for 1 hour, and then the substrate was quenched at -30°C for gelation of PVA. The thickness of the deposited PVA-H was measured by using a confocal laser displacement meter. Under the experimental conditions employed, PVA-H with a thickness over 30 μm was obtained. The thickness linearly increased with repeated dippings. The thickness of PVA-H depends on the dipping withdrawal speed, the viscosity of the PVA solution, and the diameter of the substrate. Furthermore, the thickness of PVA-H was found to be almost the same when the viscosity of the PVA solution was constant, regardless of the concentrations of PVA. These results indicate that a tubeshaped PVA-H biomodel with desired thickness and physical properties can be obtained by using a spin dip-coating technique and that PVA-H can mimic the wall thickness of various arteries and veins.

Original languageEnglish
Title of host publicationBiomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
PublisherAmerican Society of Mechanical Engineers (ASME)
Pages221-228
Number of pages8
ISBN (Print)9780791854884
DOIs
Publication statusPublished - 2011
EventASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 - Denver, CO, United States
Duration: 2011 Nov 112011 Nov 17

Publication series

NameASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
Volume2

Other

OtherASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
CountryUnited States
CityDenver, CO
Period11/11/1111/11/17

Keywords

  • Biomodel
  • Blood vessel
  • Dip-coating method
  • PVA hydrogel
  • Wall thickness

ASJC Scopus subject areas

  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Control of wall thickness of blood vessel biomodel made of poly (vinyl alcohol) hydrogel by a three-dimensional-rotating spin dip-coating method'. Together they form a unique fingerprint.

  • Cite this

    Kosukegawa, H., Kiyomitsu, C., & Ohta, M. (2011). Control of wall thickness of blood vessel biomodel made of poly (vinyl alcohol) hydrogel by a three-dimensional-rotating spin dip-coating method. In Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology (pp. 221-228). (ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011; Vol. 2). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/imece2011-64619