Control of treatment size in cavitation-enhanced high-intensity focused ultrasound using radio-frequency echo signals

Kentaro Tomiyasu, Ryo Takagi, Ryosuke Iwasaki, Shin Yoshizawa, Shin Ichiro Umemura

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

In high-intensity focused ultrasound (HIFU) treatment, controlling the ultrasound dose at each focal target spot is important because it is a problem that the length of the coagulated region in front of the focal point deviates owing to the differences in absorption in each focal target spot and attenuation in the intervening tissues. In this study, the detected changes in the power spectra of HIFU echoes were used by controlling the HIFU duration in the "trigger HIFU" sequence with the aim to increase coagulation size through the enhancement of the ultrasonic heating by the cavitation induced by the preceding extremely high intensity short "trigger" pulse. The result shows that this method can be used to detect boiling bubbles and the following generated cavitation bubbles at their early stage. By automatically stopping HIFU exposure immediately after detecting the bubbles, overheating was prevented and the deviation of the length of the coagulated region was reduced.

Original languageEnglish
Article number07JF28
JournalJapanese journal of applied physics
Volume56
Issue number7
DOIs
Publication statusPublished - 2017 Jul

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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