Control of the protein adsorption on honeycomb film by changing the pore size of honeycomb films

Hiroshi Sunami, Masaru Tanaka, Sadaaki Yamamoto, Emiko Ito, Masatsugu Shimomura

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    Micro fabrication of cell culture substrates is one of the most significant subjects in the field of biomaterial research. Recently we found that the proliferation of endothelial cells were influenced by the pore size of microporous polymer film (honeycomb film). It has been reported that adsorbed proteins on substrate play vital role in mediating cell proliferation. In order to elucidate the effect of the pore size of honeycomb films as a scaffold for cell culture, the observation of protein adsorption on honeycomb films during cell culture is needed. It was found the adsorbed protein structure on honeycomb films were greatly changed by changing pore size of honeycomb film. Further development of this approach should lead to surfaces which can control cell proliferation by changing the pore size of honeycomb films.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - 2006 Oct 19
    Event55th SPSJ Annual Meeting - Nagoya, Japan
    Duration: 2006 May 242006 May 26

    Other

    Other55th SPSJ Annual Meeting
    CountryJapan
    CityNagoya
    Period06/5/2406/5/26

    Keywords

    • AFM
    • Cell adhesion
    • Scaffold
    • Tissue engineering
    • Vascular endothelial cell

    ASJC Scopus subject areas

    • Engineering(all)

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