Construction of two-dimensional DNA-mimetics: Supramolecular architecture with highly stacked base-pairs of amphiphilic adenine and thymine at the air-water interface

F. Nakamura, K. Ijiro, Masatsugu Shimomura

    Research output: Contribution to journalArticlepeer-review

    27 Citations (Scopus)

    Abstract

    In order to construct two dimensional DNA-mimetics, nucleo base monolayers, composed of amphiphilic adenine and thymine derivatives, were prepared at the air-water interface. The monolayer were characterized by pressure-area isotherm measurements, UV-Vis absorption and FT-IR reflection-absorption spectroscopy (RAS), and fluorescence spectroscopy and microscopy. A 1:1 mixture of octadecyladenine (C18-Ade) and octadecylthymine (C18-Thy) formed the most condensed monolayer on a pure water subphase in the three combinations of the equimolar mixtures of C18-Ade, C18-Thy, and octadecylcytosine (C18-Cyt). A FT-IR RAS spectrum of the transferred monolayer suggests the base-pairing with Watson-Crick type hydrogen bondsin the C18-Ade/C18-Thy monolayer. An in situ observation of fluorescence image and spectrum at the air-water interface indicates that the Watson-Crick type monolayer canincorporate an amphi philic intercalator, octadecylacridineorange (C18-AO), as well as DNA.

    Original languageEnglish
    Pages (from-to)603-606
    Number of pages4
    JournalThin Solid Films
    Volume327-329
    Issue number1-2
    DOIs
    Publication statusPublished - 1998 Jan 1

    Keywords

    • Adenine
    • DNA mimetics
    • Fluorescence microscopy
    • Intercalation
    • Surface monolayer
    • Thymine

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Surfaces and Interfaces
    • Surfaces, Coatings and Films
    • Metals and Alloys
    • Materials Chemistry

    Fingerprint Dive into the research topics of 'Construction of two-dimensional DNA-mimetics: Supramolecular architecture with highly stacked base-pairs of amphiphilic adenine and thymine at the air-water interface'. Together they form a unique fingerprint.

    Cite this