Constant-current-mode LAPS (CLAPS) for the detection of penicillin

Tatsuo Yoshinobu; Holger Ecken; Arshak Poghossian; Anette Simonis; Hiroshi Iwasaki; Hans Lüth; Michael J. Schöning

doi:10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N

Constant-current-mode LAPS (CLAPS) for the detection of penicillin

Tatsuo Yoshinobu, Holger Ecken, Arshak Poghossian, Anette Simonis, Hiroshi Iwasaki, Hans Lüth, Michael J. Schöning

Research output: Contribution to journal › Article › peer-review

54 Citations (Scopus)

Abstract

A software feedback control system for the constant-current-mode operation of the light-addressable potentiometric sensor (LAPS) was developed. The constant-current-mode LAPS (CLAPS) is suitable for online monitoring and recording of changes in the pH value or the ion concentration. An enzyme LAPS was fabricated by adsorptive immobilization of penicillinase on the pH-sensitive layer of Ta₂O₅. This sensor was operated in the constant-current-mode and the detection limit for penicillin G was found to be at least as low as 100 μM.

Original language	English
Pages (from-to)	733-736
Number of pages	4
Journal	Electroanalysis
Volume	13
Issue number	8-9
DOIs	https://doi.org/10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N
Publication status	Published - 2001
Externally published	Yes

Keywords

CLAPS
Chemical sensor
Light-addressable potentiometric sensor (LAPS)
Penicillin
TaO

ASJC Scopus subject areas

Analytical Chemistry
Electrochemistry

Access to Document

10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N

Cite this

@article{ecc8c4c5b1a8412f85640a942aca9136,

title = "Constant-current-mode LAPS (CLAPS) for the detection of penicillin",

abstract = "A software feedback control system for the constant-current-mode operation of the light-addressable potentiometric sensor (LAPS) was developed. The constant-current-mode LAPS (CLAPS) is suitable for online monitoring and recording of changes in the pH value or the ion concentration. An enzyme LAPS was fabricated by adsorptive immobilization of penicillinase on the pH-sensitive layer of Ta2O5. This sensor was operated in the constant-current-mode and the detection limit for penicillin G was found to be at least as low as 100 μM.",

keywords = "CLAPS, Chemical sensor, Light-addressable potentiometric sensor (LAPS), Penicillin, TaO",

author = "Tatsuo Yoshinobu and Holger Ecken and Arshak Poghossian and Anette Simonis and Hiroshi Iwasaki and Hans L{\"u}th and Sch{\"o}ning, {Michael J.}",

year = "2001",

doi = "10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N",

language = "English",

volume = "13",

pages = "733--736",

journal = "Electroanalysis",

issn = "1040-0397",

publisher = "Wiley-VCH Verlag",

number = "8-9",

}

TY - JOUR

T1 - Constant-current-mode LAPS (CLAPS) for the detection of penicillin

AU - Yoshinobu, Tatsuo

AU - Ecken, Holger

AU - Poghossian, Arshak

AU - Simonis, Anette

AU - Iwasaki, Hiroshi

AU - Lüth, Hans

AU - Schöning, Michael J.

PY - 2001

Y1 - 2001

N2 - A software feedback control system for the constant-current-mode operation of the light-addressable potentiometric sensor (LAPS) was developed. The constant-current-mode LAPS (CLAPS) is suitable for online monitoring and recording of changes in the pH value or the ion concentration. An enzyme LAPS was fabricated by adsorptive immobilization of penicillinase on the pH-sensitive layer of Ta2O5. This sensor was operated in the constant-current-mode and the detection limit for penicillin G was found to be at least as low as 100 μM.

AB - A software feedback control system for the constant-current-mode operation of the light-addressable potentiometric sensor (LAPS) was developed. The constant-current-mode LAPS (CLAPS) is suitable for online monitoring and recording of changes in the pH value or the ion concentration. An enzyme LAPS was fabricated by adsorptive immobilization of penicillinase on the pH-sensitive layer of Ta2O5. This sensor was operated in the constant-current-mode and the detection limit for penicillin G was found to be at least as low as 100 μM.

KW - CLAPS

KW - Chemical sensor

KW - Light-addressable potentiometric sensor (LAPS)

KW - Penicillin

KW - TaO

UR - http://www.scopus.com/inward/record.url?scp=0034950439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034950439&partnerID=8YFLogxK

U2 - 10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N

DO - 10.1002/1521-4109(200105)13:8/9<733::AID-ELAN733>3.0.CO;2-N

M3 - Article

AN - SCOPUS:0034950439

VL - 13

SP - 733

EP - 736

JO - Electroanalysis

JF - Electroanalysis

SN - 1040-0397

IS - 8-9

ER -

Constant-current-mode LAPS (CLAPS) for the detection of penicillin

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this