Abstract
The palladium-catalyzed reaction of 2-alkynylanilines and 2-alkynylphenols in the presence of carbon monoxide and methanol under basic conditions gave the sequential cyclization / carbonylation products, methyl 2-substituted indole and benzo[b]-furan-3-carboxylates. Similar reaction of 2-alkynylbenzamides gave 3-alkylidenisoindole derivatives.
| Original language | English |
|---|---|
| Pages (from-to) | 11803-11812 |
| Number of pages | 10 |
| Journal | Tetrahedron |
| Volume | 50 |
| Issue number | 41 |
| DOIs | |
| Publication status | Published - 1994 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Fingerprint Dive into the research topics of 'Condensed heteroaromatic ring systems. XXIV. Palladium-catalyzed cyclization of 2-substituted phenylacetylenes in the presence of carbon monoxide'. Together they form a unique fingerprint.
Cite this
Kondo, Y., Shiga, F., Murata, N., Sakamoto, T., & Yamanaka, H. (1994). Condensed heteroaromatic ring systems. XXIV. Palladium-catalyzed cyclization of 2-substituted phenylacetylenes in the presence of carbon monoxide. Tetrahedron, 50(41), 11803-11812. https://doi.org/10.1016/S0040-4020(01)89295-4