Abstract
Four kinds of pyranopyridinones were synthesized from pyridinecarbonitriles containing a chlorine or bromine substituent at the adjacent position to the cyano group by the palladium-catalyzed cross-coupling reaction with terminal acetylenes followed by intramolecular cyclization with polyphosphoric acid.
Original language | English |
---|---|
Pages (from-to) | 1890-1894 |
Number of pages | 5 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 36 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1988 Jan 1 |
Keywords
- ethynylpyridinecarbonitrile
- halopyridinecarbonitrile
- palladium-catalyzed reaction
- polyphosphoric acid
- pyranopyridinone
- terminal acetylene
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery