Concise total synthesis of acortatarin A

Takaaki Teranishi, Masayuki Kageyama, Shigefumi Kuwahara

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)


    The spirocyclic pyrrole alkaloid, acortatarin A, which had been isolated from a Chinese medicinal plant, was synthesized from a known olefinic compound by a concise six-step sequence involving N-alkylation of a pyrrole derivative with an α-bromo ketone intermediate as the key step.

    Original languageEnglish
    Pages (from-to)676-678
    Number of pages3
    JournalBioscience, Biotechnology and Biochemistry
    Issue number3
    Publication statusPublished - 2013


    • Acortatarin
    • N-alkylation
    • Reactive oxygen species
    • Spiro acetal

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry


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