Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Haruhiko Fuwa; Keita Sakamoto; Takashi Muto; Makoto Sasaki

doi:10.1021/ol503491t

Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Haruhiko Fuwa, Keita Sakamoto, Takashi Muto, Makoto Sasaki

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.

Original language	English
Pages (from-to)	366-369
Number of pages	4
Journal	Organic letters
Volume	17
Issue number	2
DOIs	https://doi.org/10.1021/ol503491t
Publication status	Published - 2015 Jan 16

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol503491t

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abstract = "A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.",

author = "Haruhiko Fuwa and Keita Sakamoto and Takashi Muto and Makoto Sasaki",

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AU - Muto, Takashi

AU - Sasaki, Makoto

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Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Abstract

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