An efficient stereoselective route to (2S,4R)-4-hydroxyproline from (S)-O-benzylglycidol has been established via a novel iodine-mediated cyclization of the N-benzoyl- γ,δ-unsaturated amide.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1988 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine