Computational simulation of blood flow dynamics using an anatomically realistic artery model constructed from medical images

Yuji Shimogonya, Kazuhiro Itoh, Hiroshige Kumamaru

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Hemodynamics is believed to play a vital role in the initiation of cerebral aneurysms. In this study, we describe a newly defined hemodynamic quantity, the gradient oscillatory number (GON), as an index for the cerebral aneurysm initiation. It is defined by temporal variations of flow-induced tension/compression forces acting on endothelial cells. We calculated the index for the arterial geometry before aneurysm formation, which was constructed by artificially removing the aneurysm from a medical image-based arterial geometry. The result showed that the index had a strong correlation with the location of aneurysm formation. This suggests that the proposed index, GON, may be useful as a hemodynamic index for the initiation of cerebral aneurysms.

Original languageEnglish
Title of host publication2010 World Automation Congress, WAC 2010
Publication statusPublished - 2010 Dec 1
Event2010 World Automation Congress, WAC 2010 - Kobe, Japan
Duration: 2010 Sep 192010 Sep 23

Publication series

Name2010 World Automation Congress, WAC 2010

Other

Other2010 World Automation Congress, WAC 2010
CountryJapan
CityKobe
Period10/9/1910/9/23

Keywords

  • Blood flow
  • Cerebral aneurysm
  • Computational fluid dynamics
  • Medical image

ASJC Scopus subject areas

  • Control and Systems Engineering

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