Computational biomechanics of blood flow in cardiovascular diseases

T. Yamaguchi, T. Ishikawa, K. Tsubota, Y. Imai, D. Mori, N. Matsuki

Research output: Chapter in Book/Report/Conference proceedingChapter


Variations in both spatial and temporal scales must be considered to fully understand cardiovascular diseases. Given these considerations, we investigated the cardiovascular system from the micro- to macroscale using computational biomechanics. This paper presents our findings on mass transport in cerebral aneurysms, platelet aggregation in blood flow, and a particle method for computing microcirculation. Ultimately, these models will help to clarify the biological phenomena surrounding disease processes and will provide a framework for integrating future developments in understanding macro- and microscale biomechanics.

Original languageEnglish
Title of host publicationBiomechanics at Micro- and Nanoscale Levels
PublisherWorld Scientific Publishing Co.
Number of pages11
ISBN (Electronic)9789812771322
ISBN (Print)981277131X, 9789812771315
Publication statusPublished - 2007 Jan 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Immunology and Microbiology(all)
  • Medicine(all)

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    Yamaguchi, T., Ishikawa, T., Tsubota, K., Imai, Y., Mori, D., & Matsuki, N. (2007). Computational biomechanics of blood flow in cardiovascular diseases. In Biomechanics at Micro- and Nanoscale Levels (pp. 130-140). World Scientific Publishing Co..